Tenvir EM

Tenvir EM is a nucleoside reverse transcriptase inhibitor; this is involved in treating HIV infection. Tenvir EM tablets eliminate the HIV virus from the blood. Tenvir EM is not permanent remedy, it does not cure the disease, but it prevents AIDS. Tenvir EM is Available in various dosage forms like tablets, capsules and solution form. Tenvir EM is not under the conditions like; Pregnancy, Breastfeeding, Allergic conditions, Lactic acidosis, abnormal liver problems, Kidney problems CD 4+ cells are essential for the prevention of invasion of virus into the body. HIV is eradicate the cells and leads to cause vulnerable condition like AIDS. Tenvir EM is useful in the treatment of HIV infection, by improving the CD 4+ cells in the body

Emtricitabine and tenofovir disoproxil fumarate

Tenvir EM

200mg + 300mg



Tenvir EM is primarily indicated for; HIV infection Chronic hepatitis B virus infection


There are two major anti retroviral agents that present in Tenvir EM; contains Emtricitabine, tenofovir disoproxil fumarate.


This is one of the active ingredients of Tablet Tenvir EM , Emtricitabine is a nucleoside analog of cytidine, various cellular enzymes involved in conversion of Emtricitabine into Emtricitabine 5’-triphosphate. This conversion will prohibit the effect of HIV-1 reverse transcriptase. This binds with deoxycytidine 5’ triphosphate, mingled into viral DNA and chain termination of the cells occur.

Tenofovir disoproxil fumarate

Tenvir EM → an acyclic nucleoside phosphonate diester analog of adenosine monophosphate. Tenofovir disoproxil fumarate is converted into tenofovir by diester hydrolysis. Tenofovir is phosphorylated into tenofovir diphosphate by cellular enzymes This inhibits the effect of HIV 1 RT by competing with natural substrate (deoxyadenosine 5’-triphosphate), fusing into DNA, by DNA chain termination.


Tenvir EM is rapidly absorbed with peak plasma concentration occurring 1-2 hours.

Tenvir EM is highly bound to the human plasma protein over the range of 0.02-200 μg/mL (Emtricitabine) and 0.01–25 μg/mL (tenofovir).

Tenvir EM is metabolized and its metabolites are released through urine.

Excretion of tablet Tenvir EM occurs through urine. The mean plasma termination half-life period of tablet Tenvir EM is Emtricitabine 10 hours (7.4-18.0); tenofovir 17 hours (12.0-25.7). The bioavailability of both Emtricitabine is 92% and tenofovir is 25%


Tenvir EM
Brand Tenvir EM
Ingredients Emtricitabine and tenofovir disoproxil fumarate
Strength 200mg + 300mg
Manufactured Cipla

Tenvir EM Dosage and administration

Tenvir EM ,the dosage prescribed for the treatment of HIV infection; Tenvir EM administrated One tablet should be taken as a single dose. Tenvir EM is taken orally with or without food

The common effects caused by Tablet Tenvir EM

Gastro intestinal

diarrhea, nausea, vomiting


injection site reaction, fatigue


sinusitis, upper respiratory infection, throat infection

Central nervous system

head ache, dizziness, psychiatric disorders, depression, and sleeplessness



Common effects

Fever, chills Pain during urination Fatigue Chest pain Skin discoloration Numbness, burning or tingling (hands, arm, feet) Itching Muscle stiffness Depression

Adverse effects

Severe Acute Exacerbations of Hepatitis B New Onset or Worsening Renal Impairment. Lactic Acidosis/Severe Hepatomegaly with Steatosis Bone Effects of Tenofovir DF. Immune Reconstitution Syndrome.

Some other effects

Anorexia, Dyspepsia, asthenia, dizziness, fatigue, headache, rash, hypophosphatemia, raised liver enzymes, hepatitis, renal effects (e.g. nephritis, nephrogenic diabetes insipidus, proximal renal tubulopathy, renal failure), bone pain, osteomalacia, muscle weakness, myopathy. Rarely, raised serum amylase levels, pancreatitis, and rhabdomyolysis.


  • Coadminstration of tablet Tenvir EM with atazanavir, plasma concentration of Tenvir EM increased and the plasma concentration of atazanavir decreased.

  • Some of medicines cause drug interactions; Didanosine Ritonavir boosted Lopinavir Nephrotoxicity drugs like; cidofovir, acyclovir, valaciclovir etc


Tenvir EM should not be used in persons with unknown or positive 1 status. Tenvir EM not used as monotherapy, it is used with other retroviral medicine. Hypersensitivity in lactation

Caution should be taken while using tablet Tenvir EM , if patient having Hepatomegaly or other liver problems Renal impairment Pregnant women

The pregnancy category of Tablet Tenvir EM is comes under category B Tenvir EM should not preferred for pregnant women or become pregnant.

Tenvir EM should be stored in a cool place.


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