Xovoltib 30mg

Xovoltib 30mg is indicated for the first-line treatment for patients with metastatic non-small cell lung cancer(NSCLC)

Afatinib

Xovoltib

30mg

GSK pharmaceuticals




DESCRIPTION

Xovoltib 30mg is a type of regimen called protein kinase inhibitors.
Xovoltib 30mg is a targeted therapy drug
It used to treat non-small cell lung cancer (NSCLC). It may also be used to treat other cancers as part of clinical trial.
Xovoltib 30mg is a prescription drugs which is used under the supervision of medical practioners.

Mechanism of action

Xovoltib 30mg stops the activating sites called tyrosine kinases of various proteins within the cell. These proteins are most likely to develop cancer growth when the tumor includes the EGFR gene mutation. By stopping these targets, it will target the cancer will shrink.


drug
Brand Xovoltib
Ingredients Afatinib
Strength 30mg
Manufactured GSK pharma
Rating

Take Xovoltib on an empty stomach. Consume the drug 1 hour before or 2 hours after a meal
Avoid cutting or crushing the tablet
For adult :
The usual dose for metastatic non-small cell lung cancer is the usual dose is 40mg taken once per day.
For child :
Dosageages of 0-17 years is not being studied in children.
The drug should not be used age under 18 years of age
For renal impairment: usual dose is 30mg taken once per day.

Side effects

Xovoltib has some side effects caused like :
• Diarrhoea
• Mouth sores
• Acne
• Itchiness
• Rash
• Dry skin
• Loss of appetite
• Nausea
• Vomiting
• Nail infection.

Serious side effects

• dark coloured urine
• Bleeding or bruising
• Weakness
• Blurred vision
• Fast heartbeat
• Breathing trouble
• Cough and fever
• Yellowing the skins.

Precautions

Some patients have some serious condition ,the drug will make conditions worse, the conditions like :
Hepatic toxicity
Interstitial lung disease (ILD)
Bullous and exfoliative skin disorders
diarrhae
Embryo-fetal toxicity: Xovoltib 30mg will have risk to the foetus when administrated to pregnant women
Keratitis: if patients confirm with suspected keratitis or ulcerative keratitis then stop or discontinue the drug.

DRUG – DRUG INTERACTION

  • Xovoltib 30mg interaction with P-gpinhibitors (cyclosporine A, ketoconazole verapamil) with Xovoltib 30mg will increase exposure to Afatinib
  • Xovoltib 30mg interactionwith P-gpinducers (carbamazepine, phenytoin, phenobarbital) with Xovoltib 30mg will decrease exposure to Afatinib



Whileon treatment with Xovoltib 30mg Pregnancy should avoid becausethe drug Xovoltib 30mg is administrated to a pregnant woman will harm the foetus.

Xovoltib 30mg Excretion into human milk is unknown or will have adverse reaction in a child who is breastfed. Therefore, decision should take whether to stop breastfeeding or discontinuation of medicine.

Xovoltib 30mg Store at 25°C Keep Xovoltib 30mg away from children

If patient missed to take the dose of Xovoltib 30mg, the missed dose must be skipped and follow the regular dosing schedule Do not self-medicate.Do not double the dose Mustconsult with medical oncologist and follow the suggestions


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